Following Massive Weight Loss (MWL), various physical changes may occur due to alterations in the properties of the skin and subcutaneous tissue, separate from the weight loss itself.
In particular, skin that has been affected by severe obesity over a long period may not contract sufficiently even after weight loss, leaving behind excess skin and tissue sagging.
These changes often occur not only in one part of the body but simultaneously in multiple areas.

Changes following MWL tend to appear more readily in areas susceptible to the effects of gravity and daily activities.